WebOct 26, 2005 · Cisplatin is one of the most potent anticancer drugs used in chemotherapy (Thigpen et al., 1994; Van Basten et al., 1997).In spite of its significant anticancer activity, the clinical use of cisplatin is often limited by its undesirable side effects such as nephrotoxicity (Madias and Harrington, 1978).Hepatotoxicity can also occur when … WebCNS – Cisplatin-Lomustine-Vincristine (Packer LCV3) Cisplatin High frequency hearing loss progressing to involve the speech frequency range (500-3,000 Hz) is a major toxicity of cisplatin. It is clear that the ototoxicity is dependent upon the cumulative dose of cisplatin, but other factors such as the dose per course and drug
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WebSep 18, 2024 · National Center for Biotechnology Information WebFeb 17, 2024 · Cisplatin infusion solutions at a concentration >0.5 mg/mL may result in tissue cellulitis, fibrosis, necrosis, pain, edema, and erythema. Gastrointestinal toxicity: [US Boxed Warning]: Cisplatin can cause … safe indoor non electric heater
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Webof cisplatin with urine from healthy subjects, except that the proportions are different. The parent compound, cisplatin, is excreted in the urine and accounts for 13% to 17% of the dose excreted within one hour after administration of 50 mg/m2. The mean renal clearance of cisplatin exceeds creatinine clearance and is 62 and WebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), … WebAn "accidental" discovery leads to cisplatin.Because platinum was thought to have no biological activity, Dr. Rosenberg and his colleagues put platinum electrodes into a solution containing the common laboratory bacteria E. coli and turned on the power. As soon as the current started, the bacterial cells stopped dividing, although they kept growing to up to … ishukan communication remix