Graphene based gene transfection

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August undefined, 2024

WebMar 10, 2011 · Graphene is successfully used as a non-toxic nano-vehicle for efficient gene transfection and suggested to be a novel gene delivery nano-vector with low …

Graphene and its derivatives as biomedical materials: future …

WebApr 1, 2024 · Delivery of functional genes into stem cells shows great application prospect in DNA-based tissue engineering. However, comparing with epithelial cells and cancer cells, stem cells usually exhibit low gene transfection efficiency. To enhance the transfection efficiency, non-viral gene delivery in co … WebJan 10, 2014 · Successful gene therapy requires efficient and safe gene vectors that protect DNA from nuclease degradation as well as facilitate DNA uptake with high transfection efficiency [139], [140]. Graphene has been explored for applications in gene delivery, gene–drug co-delivery and protein delivery with good supportive literature available. songs about storms at sea

IJMS Free Full-Text Surface Functionalization with …

WebGraphene as a star in materials research has been attracting tremendous attentions in the past few years in various fields including biomedicine. In this work, for the first time we … WebDec 1, 2013 · It can be summarized through these relevant studies that GO with suitable surface functionalization could serve as gene transfection vectors for in vitro and in vivo gene delivery. However, using graphene-based nanovectors as gene transfection vectors remains to be further explored. WebApr 11, 2024 · PEI-functionalized graphene-based transporters have been widely used in gene therapy for various illnesses, including myocardial infarction, osteoporosis [188], and tumors [189]. Other agents, in addition to PEI, have been used to alter graphene-based resources for improved transfection, such as chitosan [ 173 , 184 , [190] , [191] , [192 ... songs about spring time

Gene Delivery mediated by Polyester-based Nanoparticles IJN

Efficient miRNA Inhibitor with GO-PEI Nanosheets for …

WebJun 18, 2024 · Abstract. Functionalized graphene oxide (GO) nanoparticles are being increasingly employed for designing modern drug delivery systems because of their high degree of functionalization, high surface area with … WebJan 23, 2024 · Recently graphene has been used in biomedical applications including DNA sequencing 10, biosensor development 11, and graphene-enhanced cell differentiation … songs about sticking togetherWebApr 12, 2024 · Polymeric gene carriers target the nucleus and express their therapeusis through transcription and translation . Gene carriers are either viral vectors (retro-viruses and adenoviruses) or non-viral vectors. Viral vectors submit their genetic materials to the host cells and are known to attain greater transfection . 18.3.1.2 Polymeric Micelles small farms minecraft

"WebWe conclude that modification of graphene-based nanoparticles with PEG and especially PEI provide better colloidal stability in cell medium, resulting in more uniform … " - Graphene based gene transfection

Graphene based gene transfection

Use of graphene-based materials as carriers of bioactive agents

WebDec 1, 2024 · Graphene and its derivatives, as sheet-like carbonic nanomaterials, have been progressively utilized in various biomedical fields. Currently, applications of … WebMany researchers have tried to transfect genes using carbon-based materials such as graphene oxides (GOs) and graphene quantum dots (GQDs) [29,30,31,32]. ... Prior to in vitro gene transfection with NGQDs, we verified the cytotoxicity of the NGQDs via a CCK-8 assay kit. For the CCK-8 assay, various concentrations of NGQDs from 1 μg/mL to 1000 ...

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WebNov 22, 2016 · Graphene based gene transfection. Nanoscale 2011; 3: 1252–1257. Article CAS Google Scholar Prencipe G, Tabakman SM, Welsher K, Liu Z, Goodwin AP, Zhang L et al. PEG branched polymer for ... WebVisualizing The Localization Of Transfection Complexes During Graphene Nanoparticle-Based Transfection Journal of Materials Chemistry B …

WebApr 20, 2024 · Graphene-based nanomaterials have been used as scaffolds for cell culture and tissue engineering and have exhibited minimal harmful effect on the mammalian cells, very good adhesion properties, excellent gene transfection efficacy, high capability of the promotion of differentiation of stem cells into bone cells in a controlled manner for bone ... WebDec 4, 2024 · The objective of this study is to design a graphene-based miRNA transfection drug delivery system for antiresorptive therapy. An efficient nonviral gene …

WebJan 21, 2016 · During PhD work, I extensively involved on the development of chitosan based novel non-viral vectors for gene therapy application. I developed polyamidoamine (PAMAM) dendrimer conjugated chitosan copolymer through various chemical methods and showed very high transfection efficiency. All my research works published in reputed … WebJan 27, 2011 · Degradable copolymer based on amphiphilic N-octyl-N-quatenary chitosan and low-molecular weight polyethylenimine for gene delivery. Liu C , Zhu Q , Wu W , Xu …

WebWe conclude that modification of graphene-based nanoparticles with PEG and especially PEI provide better colloidal stability in cell medium, resulting in more uniform transfection and overall increased efficiency. ... Liu, Z. Graphene based gene transfection. Nanoscale 2011, 3, 1252–1257. [Google Scholar] Liu, Z.; Robinson, J.T.; Sun, X.; Dai ...

WebThe use of NA is gaining increasing interest and more than 2000 clinical trials of NA-based therapies are underway. 2 The current advancements in medicine, biology and biotechnology have extended the scope of gene therapy from the “simple” transfection of plasmid DNA (pDNA) to the delivery of a variety of NA, including short interfering RNA ... songs about streets and roadsWebMar 1, 2011 · Graphene as a star in materials research has been attracting tremendous attentions in the past few years in various fields including biomedicine. In this work, for … small farms michiganWebFeb 28, 2024 · Feng L Zhang S Liu Z Graphene based gene transfection Nanoscale 2011 33 1252 1257 21270989 , [Web of Science ®], [Google Scholar] Yang X Wang Y Huang X Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity J Mater Chem 2011 2110 3448 3454 , [Web of Science ®], … songs about strong relationshipsWebFeng, L., Zhang, S., & Liu, Z. (2011). Graphene based gene transfection. Nanoscale, 3(3), 1252. doi:10.1039/c0nr00680g songs about staying homeWebAug 18, 2024 · Deoxyribonucleic acid (DNA) vaccines are a promising cancer immunotherapy approach. However, effective delivery of DNA to antigen-presenting cells (e.g., dendritic cells (DCs)) for the induction of an adaptive immune response is limited. Conventional DNA delivery via intramuscular, intradermal, and subcutaneous injection by … small farms network nswWebTo evaluate the transfection efficiency of NGQDs, we delivered mRNA into HeLa cells with NGQDs. As shown in Figure 4 a, the NGQDs formed complexes with mRNA at a 20:1 … small farms network capital regionWebJun 18, 2024 · Graphene-oxide-based nanocarriers have shown great potential in gene transfection and could be used in breast cancer treatments by overcoming the limitations and side effects of chemotherapy. This carbon-based material allows a facile surface modification to enhance its biological application and gene delivery efficiency. small farms network